Auditory cortex measurement with fNIRS
A little while ago we received an interesting request to measure both the temporal lobe and frontal lobe simultaneously in children with behavioral disabilities. The setup time needs to be reduced to an absolute minimum due to the behavioral nature of these children. To realize this, we came up with a combination of two of our devices, the Octamon and the Oxymon. With the Octamon the whole frontal lobe can be measured with virtually no setup time, while the Oxymon is capable of measuring in hairy areas like the temporal lobe.
As a prove of concept the auditory cortex was engaged using an auditory task. In this single participant pilot study, an activation of the auditory cortex located in the temporal lobe was observed while no major changes in oxygenation in the frontal lobe are visible. After approximately 5 seconds a clear hemodynamic response can be seen in the temporal lobe near the auditory cortex while the frontal lobe remains almost constant.
This is an example of two Artinis devices working together simultaneously, producing one single synchronized data file which can be assessed with our proprietary Oxysoft software. This can be done with any combination of Artinis devices, enabling e.g. combining simultaneous brain and muscle measurements using NIRS.
The data has been projected to the MNI-ICBM-152 (2009) template, the time range is sped up by a factor two, the position of transmitters and receivers are estimates and the color scale is optimized for contrast. This is a single participant pilot experiment, no conclusions should be drawn based on this data.
A special thanks to our customers who published so many articles with our (f)NIRS devices and we hope you will keep on publishing in the future!
The Sophia Bus was an idea pitched by researchers from the Department of Child and Adolescent Psychiatry and Psychology within Erasmus MC-Sophia Children’s Hospital. As a national expertise center for many rare neurodevelopmental syndromes, children all over the Netherlands need to travel all the way to Rotterdam frequently to participate in research studies. The Sophia bus minimizes the burden for these patients by offering the solution to this problem: a mobile research lab that carries researchers to the patients’ doorstep.
fNIRS, as a neuroimaging method, was introduced more than two decades ago. Innovation in equipment, tools, and methods based on related-neuroimaging methods is increasing thanks to several companies and academic laboratories. The use of fNIRS in future research practices will aid in advancing modern investigations of human brain function. Connectivity measures will contribute to the field of neuroscience and a multimodal imaging approach is likely required.
Thanks to the very generous gifts of local companies and private individuals during the ‘Lichtjesactie’ (translates as ‘Candles project’) that was organized during Christmas time last year by the Stichting Vrienden van Sophia, the Sophia Childrens hospital were able to buy a camper van, which has been remodeled and transformed into a mobile research lab under close guidance of dr. Sabine Mous.
We offer the full spectrum of NIRS devices, and all our devices can be mixed and matched to create your optimal setup within the same software. To aid you in finding the right device for your research we have drafted this comparative table below with the most important specifications for each device.
Watch how comfortable the Brite is, even for babies! #fNIRS
You can win a Brite system for your research project! What do you need to do? We ask you to write a short proposal, 2 pages maximum, of your research project. The most outstanding proposal will win Artinis Brite for the entire duration of your data collection period.
As an application Specialist at Artinis Medical Systems I get asked a lot what the differences are between lasers and LEDs. So, therefore a small blog to answer this question once and for all. Both laser and LED have their specific pros and cons. It depends very much on your research requirements what technique is best for you. I have broken down the differences in measuring depth, portability, pricing, wavelengths and safety in this blog.
Watch how easy setting up your Brite is!
The Brite is the only wearable fNIRS device worldwide that can measure the oxy-, deoxy- and total hemoglobin in every part of the head, e.g. prefrontal cortex, motor cortex, or visual cortex.
The artificial induction of ischemia (from Greek, meaning stopping/keeping back blood) was first shown to help protect cardiac muscle from injury in later occurring episodes of ischemia by Charles Murry and colleagues in 1986. This technique came to be called ischemic preconditioning (IPC).